COMEDIAN & PODCAST HOST Jesse Case is a popular comedian from the Nashville area who was featured on the television show The last Comic Standing. Jesse is also one of the hosts for the popular podcast Probably Science and hosts his own podcast Jesse vs. Cancer. A show that documented his winning battle with Stage 4 cancer and return to the comedy stage. Jesse and Mike talk about cancer, comedy and incompetence. They worked through a few technical difficulties, but not before some monkeys were humped.