This edition of the Brainy Gamer Podcast focuses on games that can make a difference. It features interviews with two people in the vanguard of innovative game design for social change: Suzanne Seggerman, president and co-founder of Games for Change; and Mary Flanagan, founder of the Tiltfactor Lab and Values at Play initiative. We discuss a wide range of topics, and we gear up for the G4C Festival in New York City later this month.